Outsourced Pharma App Notes & Case Studies
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Optimizing And Scaling Lentiviral Vector Production
10/23/2023
Here, we outline how the upstream and downstream workflows of the VirusExpress® platform for lentiviral vectors were optimized through the use of design of experiments and supplementary studies.
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Impact Of Glycosylation On The Effector Functions Of Monoclonal Antibodies
2/9/2024
In an example using rituximab and its biosimilars, explore the significance of minor differences of glycosylation in antibodies and its impact on their properties and functionality.
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Enhancing Ease Of Use Batch Turnaround And Process Flexibility With Single-Use TFF
6/17/2022
Use of single-use Pellicon® Capsules is an effective strategy for improving operational flexibility, product safety, and turnaround of a TFF step.
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Process Control And Performance Of A Virus Filtration System
1/12/2023
Discover a single-use automated filtration system designed to deliver robust process control and integrity assurance during the critical purification step. Explore its design features, processing control, and more.
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Applying High Throughput Processes To Optimize AAV Titers
3/8/2023
A growing number of AAV product developers are recognizing the value in moving to suspension as early in development as possible in order to optimize production.
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Accurate HC-LC Pairing And A Close-To-Nature Solution For bsAbs
9/11/2023
Examine how a proprietary technology ensures high levels of accurate HC-LC pairing without detriment to critical quality attributes such as titer, binding affinity, stability, and immunogenicity.
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Applying A Platform Approach To Bispecific Antibody Development
6/16/2023
Explore how experts were able to adjust a mAb production and purification platform to be applicable for the rapid development and scale up of a BsAb.
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Tangential Flow Filtration System Coupling To Enhance Solution Offerings
3/1/2023
Discover a simple, easy, and versatile method for capsule and depth filtration of small volumes that moves research from cell harvest to purification as quickly and efficiently as possible.
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Simplifying CHO Cell Line Genetic Stability Testing
4/11/2024
Here, we describe the use of whole genome sequencing to perform a comprehensive assessment of genetic stability in clonally derived CHO cell banks using the Aptegra™ CHO genetic stability assay.
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Engineering Approaches To Respiratory Drug Delivery
5/27/2022
Explore the material and performance properties of spray-dried and jet-milled mannitol for respiratory delivery of crystalline mannitol.