Outsourced Pharma App Notes & Case Studies
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Enhancing Ease Of Use Batch Turnaround And Process Flexibility With Single-Use TFF
6/17/2022
Use of single-use Pellicon® Capsules is an effective strategy for improving operational flexibility, product safety, and turnaround of a TFF step.
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COVID-19 Impact To Biological Drug Products Safety
6/13/2022
Review currently available literature and our recommended COVID-19 virus detection test methods and susceptibility of common biological host cells to infection.
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Developing A HIC Polishing Step For The Removal Of mAb Aggregates
9/28/2023
Learn in-depth about the development of a flow-through polishing step that employs hydrophobic interaction chromatography for the elimination of monoclonal antibody aggregates.
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Streamlining The Integrity Testing Process – From Test To Report
2/22/2023
Discover a digital transformation solution that provides first of its kind data analytics for filter integrity testing. The software helps operators and supervisors reduce time lost through review processes.
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A Transient Cell Line To Produce rAAV With Low-Level hcDNA Encapsidation
5/10/2024
Discover the ability of a novel HEK293 suspension cell line for efficient and scalable rAAV production across various serotypes with low encapsidated host cell DNA levels.
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Partnering On An Innovative Hydrogel-Based Treatment For Glioblastoma
3/22/2023
Treatments for glioblastoma multiforme (GBM) are in high demand. Learn more about the new possibilities for increased dosing and diffusion capabilities offered by nanoformed APIs.
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Overcoming Inventory Challenges For A Complex, Global Study
7/14/2022
Explore how the optimization of Interactive Response Technologies (IRT) settings relieved the burden of managing global supply needs for a CRO customer and clinical sponsor.
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Development Of A Novel Cell Culture Medium For AAV Production
9/26/2023
Explore the medium development process of a novel cell culture medium for AAV production with multiple HEK293 lineages, which was performed with three different HEK293 cell lines to maximize AAV titers.
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Bulk Filling Of Drug Substance | Accurate Aliquoting
4/24/2024
Bulk filling drug substances in traditional facilities is often a lengthy, manual process where operators are relied upon to adjust pump controls to achieve accurate filling. This method, spanning multiple shifts, increases process risk through errors that can compromise accuracy.
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Capture Of Bispecific Antibodies And Removal Of Product-Related Impurities
11/17/2022
Many antibody variants are prone to aggregation or to forming product-related impurities. Explore the application of a resin with novel selectivity to purify challenging entities.